JOURNAL ARTICLE

Recycling of purine nucleotides in legumes: functional specialization of enzyme isoforms in adenine salvage, cytokinin homeostasis, and nodulation control.

  • Published In: Journal of Experimental Botany, 2025, v. 76, n. 4. P. 913 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Becana, Manuel 3 of 3

Abstract

The article published in the Journal of Experimental Botany explores the recycling of purine nucleotides in legumes, focusing on the functional specialization of enzyme isoforms in adenine salvage, cytokinin homeostasis, and nodulation control. The study identifies two isoforms of adenine phosphoribosyltransferase (APRT) in common bean, APRT1 and APRT5, with distinct roles in adenine salvage, cytokinin metabolism, and stress responses. By utilizing CRISPR/Cas9 gene editing, the researchers demonstrate the impact of down-regulating APRT5 on nodulation, resulting in larger nodules. The findings shed light on the importance of APRT enzymes in regulating purine nucleotide recycling and their implications for plant immunity and nitrogen fixation in legumes. [Extracted from the article]

Additional Information

  • Source:Journal of Experimental Botany. 2025/02, Vol. 76, Issue 4, p913
  • Document Type:Article
  • Subject Area:Agriculture and Agribusiness
  • Publication Date:2025
  • ISSN:0022-0957
  • DOI:10.1093/jxb/eraf008
  • Accession Number:184408306
  • Copyright Statement:Copyright of Journal of Experimental Botany is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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