JOURNAL ARTICLE

HPV Associated Squamous Cell Carcinoma in the Rectal Tonsil.

  • Published In: International Journal of Surgical Pathology, 2023, v. 31, n. 3. P. 312 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Desai, Ketav; Baskovich, Brett; Alkhasawneh, Ahmad; Mohamed, Khaled; Omman, Reeba; Gopinath, Arun 3 of 3

Abstract

This article focuses on a rare case of human papillomavirus (HPV)-associated squamous cell carcinoma arising in the rectal tonsil, a localized lymphoid tissue in the rectum. The report describes a 71-year-old woman diagnosed with this carcinoma presenting as a rectal polyp, confirmed by immunohistochemical markers and high-risk HPV RNA detection. The authors highlight the rarity of HPV-related carcinomas in rectal tonsil tissue, distinguish this entity from lymphoepithelial carcinoma, and emphasize the importance of accurate nomenclature based on tumor pathogenesis. They also discuss the anatomical and histological differences between rectal tonsil and oropharyngeal tonsil, suggesting these may influence tumor behavior and prognosis. Further research is recommended to clarify the pathogenesis, biological behavior, and optimal management of these tumors.

Additional Information

  • Source:International Journal of Surgical Pathology. 2023/05, Vol. 31, Issue 3, p312
  • Document Type:Article
  • Subject Area:Anatomy and Physiology
  • Publication Date:2023
  • ISSN:1066-8969
  • DOI:10.1177/10668969221101870
  • Accession Number:163261852
  • Copyright Statement:Copyright of International Journal of Surgical Pathology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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