JOURNAL ARTICLE

Does Fibromyalgia Affect the Structure of the Dentate Gyrus?

  • Published In: QJM: An International Journal of Medicine, 2024, v. 117. P. i44 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: El Sattar Mohammed, Reem Abd; Elrakhawy, Fatma Ibrahim; El Sawy, Marwa Mohamed; Ebrahim, Sara Shawky 3 of 3

Abstract

The main focus of the article is the investigation of histological and morphometric changes in the brain and related tissues induced by various conditions and substances. One study examined the effects of anabolic androgenic steroids (AASs), synthetic derivatives of testosterone used to treat male hypogonadism, on the prefrontal cortex (PFC) and hippocampus of adult male albino rats, finding neuronal damage and astrocyte activation that partially reversed after AAS withdrawal. Another study explored structural changes in the dentate gyrus of the hippocampus in a rat model of fibromyalgia induced by repeated acidic saline injections, revealing progressive neurodegeneration and gliosis over three weeks. Additional research discussed includes the protective effects of kefir against nonalcoholic steatohepatitis (NASH) in rats via modulation of specific molecular pathways, and the association of elevated serum levels of the proinflammatory cytokine follistatin-like 1 (FSTL1) with inflammation and insulin resistance in overweight and obese children.

Additional Information

  • Source:QJM: An International Journal of Medicine. 2024/06, Vol. 117, pi44
  • Document Type:Article
  • Subject Area:Anatomy and Physiology
  • Publication Date:2024
  • ISSN:1460-2725
  • DOI:10.1093/qjmed/hcae070.101
  • Accession Number:178590274
  • Copyright Statement:Copyright of QJM: An International Journal of Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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