Impact of female sexual dysfunctions on women undergoing pipelle endometrial biopsy and endocervical curettage for abnormal uterine bleeding: a prospective cross-sectional study.

This article investigates the impact of female sexual dysfunction (FSD), depression, and anxiety on additional analgesic requirements (AAR), procedure failure (PF), and biopsy failure (BF) in women undergoing pipelle endometrial biopsy and endocervical curettage (PEB-ECC). In a prospective study of 417 women, FSD—defined per Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition; DSM-5) criteria—and anxiety (measured by the Beck Anxiety Inventory) were found to be independent predictors of increased analgesic needs during PEB-ECC. Procedure failure due to uterine inaccessibility was significantly associated with genito-pelvic pain/penetration disorder (a component of FSD), while biopsy failure was independently predicted by FSD and specifically female orgasmic disorder. The findings suggest that gynecologists and anesthesiologists should consider FSD and its components when planning and performing PEB-ECC to improve procedural success, although cultural variations and study limitations warrant cautious interpretation.