JOURNAL ARTICLE

Study of the effect of shock wave from a portable pulsed cold air plasma jet device on inactivation of Trichophyton rubrum in nails.

  • Published In: Applied Physics Letters, 2024, v. 124, n. 24. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Zhang, Ying; Chen, Zhaoquan; Shao, Changsheng; Huang, Qing 3 of 3

Abstract

This article focuses on the application of a portable pulsed cold air plasma jet (PP-CAPJ) device for treating onychomycosis, a common fungal nail infection primarily caused by Trichophyton rubrum (T. rubrum). The study demonstrates that PP-CAPJ effectively inactivates T. rubrum within human nails, with the fungicidal mechanism attributed mainly to shock waves generated by the device that disrupt fungal cell membranes without causing significant damage to the nail itself. The research further clarifies that reactive oxygen species (ROS) and ultraviolet radiation play minimal roles in fungal inactivation due to limited penetration through the nail. This work presents a noninvasive and potentially safer alternative to conventional antifungal treatments for onychomycosis.

Additional Information

  • Source:Applied Physics Letters. 2024/06, Vol. 124, Issue 24, p1
  • Document Type:Article
  • Subject Area:Anatomy and Physiology
  • Publication Date:2024
  • ISSN:0003-6951
  • DOI:10.1063/5.0206605
  • Accession Number:177896864
  • Copyright Statement:Copyright of Applied Physics Letters is the property of American Institute of Physics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.