JOURNAL ARTICLE

In vitro antiviral activity of persimmon-derived tannin against avian influenza viruses.

  • Published In: Letters in Applied Microbiology, 2023, v. 76, n. 2. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Fujimoto, Yoshikazu; Ijiri, Moe; Matsuo, Tomohide; Kawaguchi, Hiroaki 3 of 3

Abstract

This article focuses on the antiviral effects of persimmon (Diospyros kaki) tannin against avian influenza viruses. The study demonstrates that persimmon tannin at concentrations of 1.0 mg/ml or higher significantly reduces viral infectivity by over 6.0-log scale across multiple low pathogenic and highly pathogenic avian influenza virus subtypes. The antiviral mechanism involves inhibition of the hemagglutinin (HA) protein's receptor binding and membrane fusion activities, which are critical for viral infection. Given its water solubility and natural origin, persimmon tannin is proposed as a safer alternative to chemical disinfectants for inactivating avian influenza viruses in environmental water, potentially helping to prevent virus transmission among wild birds and poultry farms.

Additional Information

  • Source:Letters in Applied Microbiology. 2023/02, Vol. 76, Issue 2, p1
  • Document Type:Article
  • Subject Area:Biology
  • Publication Date:2023
  • ISSN:0266-8254
  • DOI:10.1093/lambio/ovac053
  • Accession Number:162824643
  • Copyright Statement:Copyright of Letters in Applied Microbiology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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