JOURNAL ARTICLE

Effect of maternal previous pregnancy on children's pubertal development: an 8-year pubertal cohort.

  • Published In: Human Reproduction, 2025, v. 40, n. 4. P. 675 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Zhang, Qin; Zhang, Jie; Feng, Xinyi; Wu, Di; Chen, Zixuan; Li, Yan; Liu, Qin 3 of 3

Abstract

This article investigates the influence of maternal pregnancy history, including adverse outcomes, on the pubertal development of offspring in an 8-year cohort study of 1390 children in Chongqing, China. The study found that girls born from non-first pregnancies, especially those whose mothers had prior adverse pregnancy outcomes, experienced a delayed age at menarche by approximately 0.22 years and a faster tempo of breast development compared to girls from first pregnancies. In contrast, maternal pregnancy history showed minimal impact on boys' genital development timing and tempo. These findings highlight the potential role of maternal reproductive history in shaping female pubertal progression, which may have implications for adolescent psychological and reproductive health.

Additional Information

  • Source:Human Reproduction. 2025/04, Vol. 40, Issue 4, p675
  • Document Type:Article
  • Subject Area:Biology
  • Publication Date:2025
  • ISSN:0268-1161
  • DOI:10.1093/humrep/deaf015
  • Accession Number:184323795
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