JOURNAL ARTICLE

Lipid nanoparticle–based COVID-19 vaccines: Ensuring pharmaceutical stability, safety, and efficacy.

  • Published In: American Journal of Health-System Pharmacy, 2023, v. 80, n. 24. P. 1847 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Driscoll, David F 3 of 3

Abstract

The article offers a review of U.S. Pharmacopeia (USP) chapters relating to the stability, efficacy and safety of messenger RNA (mRNA)-based lipid nanoparticle (LNP)-based COVID-19 vaccines. Topics discussed include the control of particulate matter in injections, particle size distribution (PSD) in lipid injectable emulsions, and technology for quantifying the critical large-diameter tail (LDT) region in PSD.

Additional Information

  • Source:American Journal of Health-System Pharmacy. 2023/12, Vol. 80, Issue 24, p1847
  • Document Type:Article
  • Subject Area:Business and Management
  • Publication Date:2023
  • ISSN:1079-2082
  • DOI:10.1093/ajhp/zxad221
  • Accession Number:174081740

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