A postmortem case report involving fentanyl, desalkylgidazepam, and bromazolam.

This article focuses on the toxicological analysis of two new psychoactive substances (NPS) designer benzodiazepines, desalkylgidazepam and bromazolam, in a fatal intoxication case involving a 24-year-old male. Using gas chromatography coupled with mass spectrometry (GC–MS), the study quantified high concentrations of desalkylgidazepam (1100 ng/mL) and bromazolam (352 ng/mL) in postmortem blood, alongside fentanyl, indicating polydrug use consistent with emerging trends in illicit drug markets. The findings highlight the challenges in detecting and interpreting the toxicological impact of these substances, which often appear in combination with opioids, contributing to overdose deaths. This work provides validated analytical methods and concentration data to assist forensic toxicologists in identifying and quantifying these NPS benzodiazepines in future casework.