JOURNAL ARTICLE

Numerical Analysis of the Influence of Driver Gases on the Penetration Depth of Particles Using a Micro-Shock Tube-Based Needle-Free Delivery Device.

  • Published In: International Journal of Computational Methods, 2025, v. 22, n. 7. P. 1 1 of 3

  • Database: Applied Science & Technology Source Ultimate 2 of 3

  • Authored By: Srivastava, Ayushman; Kundu, Abhishek; Ranjan Paul, Akshoy 3 of 3

Abstract

The drug powder is delivered using a micro-shock tube device into the human body without utilizing the needles. The effect of different driver gases is poorly understood. We considered three different driver gases, i.e., air, helium, and argon. Numerical simulations were conducted, and the penetration depth achieved by the drug particle was calculated using the formula available in the existing literature. The simulation outcomes were then compared to the practical results to validate the solver. It was observed that the helium gas propelled the particles at a high velocity compared to air and argon, confirming the particle's higher penetration depth. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:International Journal of Computational Methods. 2025/09, Vol. 22, Issue 7, p1
  • Document Type:Article
  • Subject Area:Chemistry
  • Publication Date:2025
  • ISSN:02198762
  • DOI:10.1142/S0219876225500136
  • Accession Number:185494412
  • Copyright Statement:Copyright of International Journal of Computational Methods is the property of World Scientific Publishing Company and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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