A New CuI/Oxalamide Catalytic System for the Large‐Scale Aerobic Oxidation of Alcohols.

  • Published In: European Journal of Organic Chemistry, 2024, v. 27, n. 46. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Xing, Kexue; Xiang, Jicong; Luo, Zijin; Liu, Guiyuan; Zhang, Xianghao; Zhang, Guofu; Ding, Chengrong 3 of 3

Abstract

Since the report of oxamide ligands, they have been widely used for the efficient construction of various types of C−X (such as C, N, O and S) bonds. To evaluate whether the easily tunable electronic properties and unique coordination modes of oxamide ligands can also shine in the field of oxidation, we initiated a study on oxamide ligand/copper/air oxidation and applied it to the oxidation of alcohols to assess its practicality and potential applications. The practicality of this strategy was further verified through scale‐up reactions on a 100 mmol scale and gram‐scale derivatization of pharmaceutical molecules. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:European Journal of Organic Chemistry. 2024/12, Vol. 27, Issue 46, p1
  • Document Type:Article
  • Subject Area:Chemistry
  • Publication Date:2024
  • ISSN:1434-193X
  • DOI:10.1002/ejoc.202400804
  • Accession Number:181731131
  • Copyright Statement:Copyright of European Journal of Organic Chemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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