JOURNAL ARTICLE

A new lupane glycoside isolated from Dendrobium officinale with α‐glucosidase inhibitory activity.

  • Published In: Vietnam Journal of Chemistry, 2025, v. 63, n. 5. P. 810 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Yen, Pham Hai; Hang, Dan Thi Thuy; Tra, Dinh Thu; Hoang, Nguyen Huy; Bang, Ngo Anh; Dung, Nguyen Viet; Huong, Phan Thi Thanh; Yen, Duong Thi Hai; Dung, Duong Thi; Trang, Do Thi; Tai, Bui Huu; Kiem, Phan Van 3 of 3

Abstract

A new lupane triterpene glycoside (1) and four known compounds (2‐5) were isolated from the aerial parts of Dendrobium officinale. Their chemical structures were determined to be 3‐O‐α‐L‐arabinopyranosylbetulinic acid 28‐O‐β‐D‐glucopyranosyl‐(1→6)‐β‐D‐glucopyranosyl ester (1), 3‐O‐α‐L‐arabinopyranosylbetulinic acid 28‐O‐α‐L‐rhamnopyranosyl‐(1→4)‐β‐D‐glucopyranosyl‐(1→6)‐β‐ D‐glucopyranosyl ester (2), 3‐O‐β‐D‐glucopyranosylbetulinic acid 28‐O‐α‐L‐rhamnopyranosyl‐(1→4)‐β‐D‐glucopyranosyl‐(1→6)‐β‐D‐glucopyranosyl ester (3), 6α‐hydroxylup‐20(29)‐en‐3‐on 28‐oic acid (4), and lupeol (5) by analyzing the HR‐ESI‐MS, 1D and 2D NMR spectra including COSY and NOESY. Compounds 1, 2 and 4 showed weak α‐glucosidase inhibitory activity with IC50 values ranging from 87.5 to 98.2 µM. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Vietnam Journal of Chemistry. 2025/10, Vol. 63, Issue 5, p810
  • Document Type:Article
  • Subject Area:Chemistry
  • Publication Date:2025
  • ISSN:0866-7144
  • DOI:10.1002/vjch.70020
  • Accession Number:188672294
  • Copyright Statement:Copyright of Vietnam Journal of Chemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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