Well Defined Phosphine Free Ni‐Catalyzed Dehydrogenation of Secondary Alcohols for the Synthesis of Ketones and Ketazines.

  • Published In: Chemistry - An Asian Journal, 2024, v. 19, n. 24. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Maji, Ankur; Singh, Ovender; Sharma, Keshav; Kumari, Sheela; Ghosh, Kaushik 3 of 3

Abstract

In this work, we unveil a novel synthesis of bench stable Ni (II) complexes supported by tetradentate Schiff‐base ligands and the complexes were devoid of any phosphine or phosphine‐based ligand. These Ni‐complexes were successfully applied for the dehydrogenation of secondary alcohols for ketone and ketazine syntheses. Secondary alcohols with different functional groups were well tolerated during catalytic cycle. Moreover, we successfully extended this protocol for the synthesis of biologically significant ketones and ketazines. On the basis of various control experiments, probable reaction pathway was proposed, and an acceptorless alcohol dehydrogenation mechanism was suggested. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Chemistry - An Asian Journal. 2024/12, Vol. 19, Issue 24, p1
  • Document Type:Article
  • Subject Area:Chemistry
  • Publication Date:2024
  • ISSN:1861-4728
  • DOI:10.1002/asia.202400818
  • Accession Number:181662682
  • Copyright Statement:Copyright of Chemistry - An Asian Journal is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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