JOURNAL ARTICLE

Transition‐Metal Free, One Pot Synthesis of Selenoesters via Reaction of Alkyl Selenides and Acyl Chlorides.

  • Published In: Asian Journal of Organic Chemistry, 2023, v. 12, n. 12. P. 1 1 of 3

  • Database: Applied Science & Technology Source Ultimate 2 of 3

  • Authored By: Duarte, Juliana S.; De Oliveira, Sandynara A.; Da Silva, Emily C. O.; De Jesus, Andreia P. V.; Vasconcelos, Leonardo G.; De Sousa Júnior, Paulo T.; Rafique, Jamal; Saba, Sumbal; Stein, André L. 3 of 3

Abstract

Herein, we report a new and efficient method for the synthesis of selenoesters by a direct coupling reaction of alkyl selenides with acyl chlorides in ethanol under transition metal‐free conditions. This nucleophilic acyl substitution afforded selenoesters in good yields. Traditionally, synthesis of selenoesters involve the reaction of acyl chlorides with an organoselenium anions generated in situ through the reductive cleavage of previously prepared diselenides. Our one‐pot approach avoids the pre‐preparation of diselenides and operated in atom‐economical and environmentally friendly conditions. The synthetic utility of these selenoesters was studied using Se‐butyl benzoselenoate as substrate in a Sonogashira‐type cross‐coupling reaction. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Asian Journal of Organic Chemistry. 2023/12, Vol. 12, Issue 12, p1
  • Document Type:Article
  • Subject Area:Chemistry
  • Publication Date:2023
  • ISSN:21935807
  • DOI:10.1002/ajoc.202300474
  • Accession Number:174515292
  • Copyright Statement:Copyright of Asian Journal of Organic Chemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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