Wire- and radiofrequency identification tag-guided localization of impalpable breast lesions: iBRA-NET localization study.

This article reports on the iBRA-NET localization study, a large UK-based, multicentre observational cohort study comparing radiofrequency identification (RFID) tag-guided localization with traditional wire-guided localization for impalpable breast lesions prior to breast-conserving surgery. The study found that RFID localization is similarly effective and safe as wire-guided localization, with comparable lesion identification rates and complication profiles, although RFID showed a higher rate of device dislodgement during surgery. Secondary surgical outcomes, including margin positivity and re-excision rates, were largely equivalent between the two methods, suggesting that surgical outcomes may depend more on disease characteristics than localization technique. The study highlights potential logistical advantages of RFID localization, such as scheduling flexibility, while noting limitations including its observational design and lack of cost-effectiveness or patient satisfaction data.