Saffron and retinal neurodegenerative diseases: Relevance of chemical composition.

  • Published In: Journal of Anatomy, 2023, v. 243, n. 2. P. 265 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Maggi, Maria A.; Consonni, Roberto; Cagliani, Laura R.; Prestipino, Gianfranco; Bisti, Silvia; Picco, Cristiana 3 of 3

Abstract

Saffron is an ancient spice largely used in traditional medicine. It has been found to be effective in treatment of retinal neurodegenerative diseases like age‐related macular degeneration and Stargardt. In the present manuscript, it is shown that saffron's neuroprotective power is strongly related to the bioactivity of all its chemical components. Nuclear magnetic resonance spectroscopy and "in vitro" experiments confirm the relevance of crocins for saffron efficacy. These results underline the importance of strictly defining the chemical composition of the natural compounds in saffron to optimize their effectiveness in the treatment of diseases. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Journal of Anatomy. 2023/08, Vol. 243, Issue 2, p265
  • Document Type:Article
  • Subject Area:Complementary and Alternative Medicine
  • Publication Date:2023
  • ISSN:0021-8782
  • DOI:10.1111/joa.13722
  • Accession Number:164876854
  • Copyright Statement:Copyright of Journal of Anatomy is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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