JOURNAL ARTICLE

Researchers from National Institute of Mental Health (NIMH) Discuss Findings in Attention Deficit Hyperactivity Disorders (Developmental trajectories of glutamate and the variable clinical course of ADHD in youth).

  • Published In: Mental Health Weekly Digest, 2026. P. 1338 1 of 2

  • Database: Psychology Source 2 of 2

Abstract

The article focuses on research investigating the role of glutamate, a major excitatory neurotransmitter, in Attention Deficit Hyperactivity Disorder (ADHD) and its variable clinical courses. Conducted by researchers in Bethesda, Maryland, the study analyzed glutamate levels in the medial prefrontal cortex of 161 participants, including those with persistent ADHD, remitting ADHD, and unaffected controls. Findings indicated that individuals with persistent ADHD exhibited an age-related increase in glutamate, contrasting with a decrease observed in those who remitted and the controls. This suggests that altered glutamate maturation may influence the persistence of ADHD symptoms into adulthood. [Extracted from the article]

Additional Information

  • Source:Mental Health Weekly Digest. 2026/02, p1338
  • Document Type:Article
  • Subject Area:Complementary and Alternative Medicine
  • Publication Date:2026
  • ISSN:1543-6616
  • Accession Number:191721977
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