JOURNAL ARTICLE

Comment on: Deleterious effects of a combination therapy using fluoroquinolones and tetracyclines for the treatment of Japanese spotted fever: a retrospective cohort study based on a Japanese hospital database.

  • Published In: Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 11. P. 3049 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Itoh, Kazuhiro; Tsutani, Hiroshi; Kabata, Daijiro; Sakabe, Shigetoshi; Mitsuke, Yasuhiko; Iwasaki, Hiromichi 3 of 3

Abstract

The article in the Journal of Antimicrobial Chemotherapy discusses concerns regarding a study on the treatment of Japanese spotted fever using a combination of fluoroquinolones and tetracyclines. The authors question the use of the term 'deleterious' in the study title and raise issues about diagnostic accuracy, potential connections between antibiotics and convulsions, and the confounding relationship between severe JSF and fluoroquinolone usage. They suggest that combination therapy can lead to rapid symptom improvement and reduced treatment duration, but caution against the use of non-steroidal anti-inflammatory drugs in JSF cases. The study emphasizes the need for further research to accurately evaluate the effects of fluoroquinolones in treating JSF. [Extracted from the article]

Additional Information

  • Source:Journal of Antimicrobial Chemotherapy (JAC). 2024/11, Vol. 79, Issue 11, p3049
  • Document Type:Article
  • Subject Area:Complementary and Alternative Medicine
  • Publication Date:2024
  • ISSN:0305-7453
  • DOI:10.1093/jac/dkae352
  • Accession Number:180625972
  • Copyright Statement:Copyright of Journal of Antimicrobial Chemotherapy (JAC) is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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