JOURNAL ARTICLE

Transcriptional analysis provides molecular insights into degeneration of the edible fungus Flammulina filiformis.

  • Published In: Journal of Applied Microbiology, 2025, v. 136, n. 3. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Wang, Caiyi; Sun, Yu; Yang, Xinyu; Wang, Zehao; Xiang, Shibo; Huang, Zhuqing; Liang, Yue 3 of 3

Abstract

This article focuses on the molecular mechanisms and detection of strain degeneration in Flammulina filiformis, a widely cultivated edible mushroom. The study compares a cultivated strain (F1) and its subcultured derivative (F7), finding that degeneration manifests as reduced fruiting body production despite similar mycelial growth. Transcriptome analysis identified differentially expressed genes enriched in oxidoreductase activity and peroxisome pathways, implicating oxidative stress regulation in degeneration. Based on these findings, the authors developed a stress tolerance assay that detects degeneration earlier than morphological changes, offering a practical tool for strain selection in industrial cultivation of F. filiformis.

Additional Information

  • Source:Journal of Applied Microbiology. 2025/03, Vol. 136, Issue 3, p1
  • Document Type:Article
  • Subject Area:Complementary and Alternative Medicine
  • Publication Date:2025
  • ISSN:1364-5072
  • DOI:10.1093/jambio/lxaf039
  • Accession Number:184351048
  • Copyright Statement:Copyright of Journal of Applied Microbiology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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