Unveiling the Potential of Cell Line Models in Homeopathic Research: A Review.

Background • Cell line models are indispensable in modern biomedical research, investigating cell functions and disease mechanisms. Recent studies have explored the impact of homeopathic treatments on cell lines, providing insights into their effects on differentiation, biomarker release, cytotoxicity, proliferation, and inhibition. Integrating homeopathy and cell studies enhances evidence-based practices, deepens mechanism understanding, and boosts treatment credibility and applicability. Objective • To evaluate the interaction between homeopathic medicines and cell line models, and explore potential applications and implications for evidence-based homeopathic research. Material and Method • The present study is a systematic literature review. A literature search was conducted in electronic databases, including PubMed, SOCPUS, and Google Scholar, using combinations of keywords. The following inclusion criteria were used: studies involving cell line models; incorporating homeopathic treatments; presenting empirical data on cytotoxicity proliferation, or inhibition; and being published in peer-reviewed Englishlanguage scientific journals. Observation/Discussion • Symphytum officinale enhanced bone healing and regeneration in mesenchymal stem cells. Homeopathic Viscum album showed positive results in breast cancer cytotoxicity. Homeopathic preparations boosted natural killer cell activity in a cancer cell line. Viscum album extract has the potential for osteosarcoma treatment while ultra-diluted remedies induce breast cancer cell apoptosis. Conclusion • The reviewed studies emphasize homeopathic potential in regenerative medicine, cancer therapy, and immune modulation. More research is needed to assess their clinical safety and efficacy. These findings help to advance targeted treatments, opening new medical research and practice avenues. [ABSTRACT FROM AUTHOR]