JOURNAL ARTICLE

Evaluation of Tissue and Serum Levels of Interleukin-15 in Non-Segmental Vitiligo.

  • Published In: QJM: An International Journal of Medicine, 2024, v. 117. P. ii89 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Abdelaziem, Manar Ashraf; Ragab, Nader Fouad; Salem, Lamyaa; El-Khateeb, Ekramy Ahmed 3 of 3

Abstract

The article focuses on the evaluation of tissue and serum levels of Interleukin-15 (IL-15) in patients with non-segmental vitiligo, an autoimmune skin depigmentation disorder. A case-control study involving 20 vitiligo patients and 11 controls measured IL-15 levels using ELISA in serum and skin biopsies from active, stable, and recurrent vitiliginous patches. Results showed significantly higher IL-15 levels in patients compared to controls, with the highest levels found in recurrent patches, suggesting IL-15's role in the pathogenesis, activity, and recurrence of vitiligo. The findings indicate that IL-15 could be a potential therapeutic target for managing and preventing vitiligo recurrence.

Additional Information

  • Source:QJM: An International Journal of Medicine. 2024/10, Vol. 117, pii89
  • Document Type:Article
  • Subject Area:Complementary and Alternative Medicine
  • Publication Date:2024
  • ISSN:1460-2725
  • DOI:10.1093/qjmed/hcae175.208
  • Accession Number:181635828
  • Copyright Statement:Copyright of QJM: An International Journal of Medicine is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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