JOURNAL ARTICLE

Effects of conjugated linoleic acid and exercise on body composition and obesity: a systematic review and meta-analysis.

  • Published In: Nutrition Reviews, 2023, v. 81, n. 4. P. 397 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Liang, Chun-Wei; Cheng, Hsiao-Yi; Lee, Yu-Hao; Liou, Tsan-Hon; Liao, Chun-De; Huang, Shih-Wei 3 of 3

Abstract

This article systematically reviews and meta-analyzes the synergistic effects of conjugated linoleic acid (CLA) supplementation combined with exercise on body composition, exercise-related indices, insulin resistance, lipid profiles, and safety. Based on 20 clinical trials involving CLA isomers (primarily cis-9, trans-11 and trans-10, cis-12) combined with various exercise regimens, the analysis found that CLA plus exercise significantly reduces body fat and insulin resistance compared to exercise alone, particularly in overweight or obese individuals and women, with longer intervention durations (>4 weeks) showing greater benefits. However, CLA supplementation did not significantly affect body weight, muscle strength, exercise performance, or lipid profiles beyond the effects of exercise alone. CLA combined with exercise was generally safe, with no increased risk of adverse events reported. The study highlights the need for further research on CLA isomer-specific effects, mechanisms underlying sex differences, and long-term outcomes.

Additional Information

  • Source:Nutrition Reviews. 2023/04, Vol. 81, Issue 4, p397
  • Document Type:Article
  • Subject Area:Complementary and Alternative Medicine
  • Publication Date:2023
  • ISSN:0029-6643
  • DOI:10.1093/nutrit/nuac060
  • Accession Number:162394340
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