Modulatory mechanisms of electroacupuncture in fascial tissue repair: a pilot study using a rat model of thoracolumbar fasciitis.

This article focuses on the effects of electroacupuncture (EA) at acupuncture points BL23 (Shenshu) and BL40 (Weizhong) on fascial tissue repair in a rat model of thoracolumbar fasciitis (TLF). The study found that EA reduced mechanical pain sensitivity, fascial thickness, inflammatory markers (tumor necrosis factor-α and interleukin-1β), and fibroblast activation, while promoting a favorable balance in extracellular matrix components. These therapeutic effects are associated with modulation of the transforming growth factor (TGF)-β1/suppressor of mother against decapentaplegic (Smad)2 signaling pathway. The findings suggest that EA may aid in reducing inflammation and fibrosis, thereby supporting fascial repair and offering potential for managing myofasciitis-related musculoskeletal pain.