JOURNAL ARTICLE

Clinical decision support systems for heart failure management optimization: A systematic review and meta-analysis of randomized controlled trials.

  • Published In: Journal of Telemedicine & Telecare, 2026, v. 32, n. 2. P. 85 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Khan, Ubaid; Amin, Ahmed Mazen; Khlidj, Yehya; Majeed, Zuhair; Ayyad, Mohammed; Al-shammari, Ali Saad; Imran, Muhammad; Ali, Junaid; Abuelazm, Mohamed 3 of 3

Abstract

This article systematically reviews and meta-analyzes randomized controlled trials (RCTs) assessing the efficacy of clinical decision support systems (CDSS) in managing heart failure (HF) patients. CDSS use was associated with a significant reduction in all-cause mortality and an increased prescription of mineralocorticoid receptor antagonists (MRA), but showed no significant effect on all-cause hospitalization or the initiation of all classes of guideline-directed medical therapy (GDMT). The evidence is limited by small sample sizes, heterogeneity among studies, and short follow-up durations, leading to very low to moderate certainty in outcomes. The findings suggest that while CDSS may enhance certain aspects of HF management, further robust, long-term studies are needed to confirm their clinical benefits and optimize their implementation.

Additional Information

  • Source:Journal of Telemedicine & Telecare. 2026/02, Vol. 32, Issue 2, p85
  • Document Type:Article
  • Subject Area:Computer Science
  • Publication Date:2026
  • ISSN:1357-633X
  • DOI:10.1177/1357633X251323489
  • Accession Number:191515768
  • Copyright Statement:Copyright of Journal of Telemedicine & Telecare is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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