JOURNAL ARTICLE

Therapeutic failure in leprosy, French Guiana, 2011–2024: Impact of bacillary index.

  • Published In: Journal of the European Academy of Dermatology & Venereology, 2026, v. 40, n. 1. P. e27 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Boscals de Réals, Quiterie; Lebret, Juliette; Drak Alsibai, Kinan; Blaizot, Romain; Grotta, Geoffrey 3 of 3

Abstract

The article focuses on the high rates of treatment failure and relapse in leprosy patients in French Guiana, with an overall failure rate of 43%. The study analyzed 125 patients diagnosed between 2011 and 2014, revealing discrepancies between WHO classifications and histological findings, as well as a significant association between a high bacillary index (BI) and treatment failure or relapse. The findings suggest that the current treatment durations recommended by the WHO may be insufficient, particularly for multibacillary patients with a BI of 3 or more, and propose extending treatment durations to improve outcomes. The study emphasizes the need for personalized treatment approaches based on more accurate predictive factors. [Extracted from the article]

Additional Information

  • Source:Journal of the European Academy of Dermatology & Venereology. 2026/01, Vol. 40, Issue 1, pe27
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2026
  • ISSN:0926-9959
  • DOI:10.1111/jdv.20744
  • Accession Number:190444404
  • Copyright Statement:Copyright of Journal of the European Academy of Dermatology & Venereology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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