JOURNAL ARTICLE

Multiple lymphadenopathies in eosinophilic granulomatosis with polyangiitis: Differentiating from IgG4-related lymphadenopathy.

  • Published In: Modern Rheumatology Case Reports, 2024, v. 8, n. 2. P. 318 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Jun-ichi Kurashina; Yasuhiro Shimojima; Dai Kishida; Takanori Ichikawa; Takeshi Uehara; Yoshiki Sekijima 3 of 3

Abstract

This article presents a case study of a 75-year-old man with eosinophilic granulomatosis with polyangiitis (EGPA) who had multiple lymphadenopathies. The lymph node tissue biopsy revealed features of both EGPA and IgG4-related lymphadenopathy (IgG4-LAD). While IgG4-LAD is a distinct clinical category, some autoimmune diseases like EGPA can have similar lymphadenopathies. The presence of IgG4-positive plasma cells suggests a potential connection between EGPA and IgG4-related disease (IgG4-RD). The article also mentions the coexistence of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis and IgG4-RD in some cases, as well as the role of hypocomplementemia in disease activity. [Extracted from the article]

Additional Information

  • Source:Modern Rheumatology Case Reports. 2024/07, Vol. 8, Issue 2, p318
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2024
  • ISSN:2472-5625
  • DOI:10.1093/mrcr/rxae022
  • Accession Number:178758617
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