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Complement.

  • Published In: Arthritis & Rheumatology, 2024, v. 76, n. 1. P. 1 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Monach, Paul A. 3 of 3

Abstract

The role of complement in human autoimmune, inflammatory, and infectious diseases is reviewed, focusing on clinical applicability. A typical case is presented in which serum testing for C3 and C4 is performed to help assess a syndrome with a broad differential diagnosis. The review includes a discussion of complement deficiency states, consumption of complement by diseases characterized by immune‐complex formation and deposition, usefulness and interpretation of laboratory tests for complement, and development of drugs targeting specific components of the complement pathway for a growing number of indications. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Arthritis & Rheumatology. 2024/01, Vol. 76, Issue 1, p1
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2024
  • ISSN:2326-5191
  • DOI:10.1002/art.42671
  • Accession Number:174515367
  • Copyright Statement:Copyright of Arthritis & Rheumatology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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