Amitriptyline at low dose for burning mouth syndrome.

The article discusses the use of low-dose amitriptyline as a treatment for burning mouth syndrome (BMS), emphasizing its potential effectiveness based on a retrospective study. Topics discussed include the pharmacological action of amitriptyline in relation to serotonin and pain modulation, the neurological mechanisms involved in chronic pain and nociplastic pain, and the significance of brain network connectivity in managing pain associated with BMS.