JOURNAL ARTICLE

Unorthodox 'universal vaccine' offers broad protection in mice: Immune-stimulating cocktail could shield against diverse bacterial and viral infections.

  • Published In: Sciencemag.org, 2026. P. N.PAG 1 of 3

  • Database: Applied Science & Technology Source Ultimate 2 of 3

  • Authored By: Leslie, Mitch 3 of 3

Abstract

The article discusses a new approach to creating a "universal vaccine" that could provide broad protection against various bacterial and viral infections, including SARS-CoV-2. Researchers developed a nasal spray containing immune-stimulating compounds that successfully protected mice from respiratory pathogens and reduced inflammation and tissue damage. The formulation, which includes adjuvants and ovalbumin, enhances both the innate and adaptive immune responses, with macrophages playing a crucial role in fighting infections. The team plans to test a modified version of this approach in humans, aiming to replace ovalbumin with a SARS-CoV-2 antigen to further stimulate immune defenses. [Extracted from the article]

Additional Information

  • Source:Sciencemag.org. 2026/02, pN.PAG
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2026
  • Accession Number:191766946
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