JOURNAL ARTICLE

Systemic anti‐inflammatory therapy in congenital ichthyosis: Real‐world experience in a series of 22 cases.

  • Published In: Journal of the European Academy of Dermatology & Venereology, 2025, v. 39, n. 5. P. e444 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Trefzer, Laura Katharina; Davidovic, Miodrag; Li, Donglin; Karakioulaki, Meropi; Casetti, Federica; Schempp, Christoph M.; Eyerich, Kilian; Has, Cristina 3 of 3

Abstract

The article discusses the use of systemic anti-inflammatory therapies in treating congenital ichthyosis, a condition characterized by generalized scaling and inflammation. A retrospective study of 22 patients showed that most patients experienced benefits from anti-inflammatory treatments, leading to a decrease in disease severity and itch intensity. Different drugs targeting Type 2 and Type 3 inflammation had varying effects on symptoms, with IL-17A-positive inflammatory infiltrate predicting responses to specific treatments. The study highlights the potential of systemic anti-inflammatory therapies for managing genodermatoses and calls for further research in this area. [Extracted from the article]

Additional Information

  • Source:Journal of the European Academy of Dermatology & Venereology. 2025/05, Vol. 39, Issue 5, pe444
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2025
  • ISSN:0926-9959
  • DOI:10.1111/jdv.20482
  • Accession Number:184767410
  • Copyright Statement:Copyright of Journal of the European Academy of Dermatology & Venereology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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