Prevalence and influencing factors of depressive and anxiety symptoms among hospital-based healthcare workers during the surge period of the COVID-19 pandemic in the Chinese mainland: a multicenter cross-sectional study.

This article focuses on the mental health status of hospital-based healthcare workers (HCWs) in mainland China during the COVID-19 surge from November 2022 to February 2023. A multicenter cross-sectional study involving 6,522 HCWs found a high prevalence of depressive symptoms (70.75%) and anxiety symptoms (47.87%) during this period. Factors positively associated with these symptoms included female gender, longer working years, COVID-19 infection, perceived higher risk of infection, increased work intensity, and supporting unfamiliar departments. Protective factors identified were higher levels of mindfulness, resilience (measured by the Connor–Davidson Resilience Scale), and perceived social support. The study suggests tailored interventions such as mindfulness practice and institutional support to mitigate psychological distress among HCWs during current and future infectious disease outbreaks.