JOURNAL ARTICLE

Utility of Anaerobic Blood Cultures in Neonatal Sepsis Evaluation.

  • Published In: Journal of the Pediatric Infectious Diseases Society, 2024, v. 13, n. 8. P. 406 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Gottschalk, Amanda; Coggins, Sarah; Dhudasia, Miren B; Flannery, Dustin D; Healy, Tracy; Puopolo, Karen M; Gerber, Jeffrey; Mukhopadhyay, Sagori 3 of 3

Abstract

This article examines the clinical utility of anaerobic blood culture bottles in neonatal sepsis evaluations within a Level-III neonatal intensive care unit (NICU). In a retrospective study of 4599 blood cultures from 3665 infants over eight years, pathogens were recovered exclusively in anaerobic bottles in 17.6% of positive paired cultures, including obligate anaerobes and facultative anaerobes such as coagulase-negative staphylococci, Escherichia coli, and Staphylococcus aureus. Additionally, when both aerobic and anaerobic bottles were positive, the anaerobic bottle more frequently yielded faster pathogen detection. The findings suggest that including anaerobic blood cultures may enhance pathogen recovery and speed of diagnosis in NICU patients, potentially informing antibiotic management despite concerns about cost and blood volume requirements.

Additional Information

  • Source:Journal of the Pediatric Infectious Diseases Society. 2024/08, Vol. 13, Issue 8, p406
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2024
  • ISSN:2048-7193
  • DOI:10.1093/jpids/piae056
  • Accession Number:179243310
  • Copyright Statement:Copyright of Journal of the Pediatric Infectious Diseases Society is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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