JOURNAL ARTICLE

Topical Hesperidin Loaded Nanosponges Gel: The Future of Impetigo Treatment in Cosmetology.

  • Published In: Journal of Cosmetic Science, 2025, v. 76, n. 5. P. 389 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: KHAN, AFRIN; PANDIT, ASHLESHA P.; DHARADHIKARI, NAMRATA 3 of 3

Abstract

Hesperidin shows antibacterial and anti-inflammatory activities. The current study intended to explore antibacterial activity of hesperidin loaded nanosponge gel for impetigo treatment. Nanosponges were prepared through the emulsion solvent diffusion method using a three level, two-factor, full factorial design (dichloromethane-8, 9, 10 mL, ethyl cellulose-1:5, 1:7, 1:9, and polyvinyl alcohol). Further, Field Emission Scanning Electron Microscopy revealed that spherically shaped porous nanosponges produced good production yield (68 ± 0.82%), high entrapment efficiency (82.8 ± 1.21%), and drug release (94.03 ± 0.96) within 2.5 hours. Furthermore, antibacterial activity against S. aureus showed that hesperidin loaded nanosponge gel exhibited a larger zone of inhibition (39 mm ± 1) than hesperidin gel (27 mm ± 2) and marketed gel (28mm ± 1), therefore, confirming the effects of nanosponges. Thus, hesperidin loaded nanosponges gel exhibited a notable impact on Staphylococcus aureus which impacts the future of impetigo treatment in cosmetology. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:Journal of Cosmetic Science. 2025/09, Vol. 76, Issue 5, p389
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2025
  • ISSN:1525-7886
  • Accession Number:190394919
  • Copyright Statement:Copyright of Journal of Cosmetic Science is the property of Society of Cosmetic Chemists and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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