Successful completion of orthodontic therapy in a patient with osteopetrosis: Case Report.

This article focuses on the orthodontic management of a 14-year-old female patient diagnosed with polyostotic osteopetrosis (OP), a rare inherited metabolic bone disorder characterized by abnormally dense, poorly vascularized bone. Despite historical contraindications for orthodontic therapy in OP due to risks of infection and osteomyelitis, the patient underwent comprehensive fixed orthodontic treatment over three years without osseous complications, achieving improved dental alignment with minor residual malocclusion. The report highlights challenges such as prolonged treatment duration, difficulty in cephalometric analysis due to dense bone, and the need for reduced orthodontic forces and close monitoring to mitigate adverse outcomes. This case represents only the second published account of completed orthodontic therapy in an OP patient, underscoring the importance of multidisciplinary evaluation and cautious treatment planning in such complex cases.