JOURNAL ARTICLE

Progressive multifocal leukoencephalopathy in multiple myeloma.

  • Published In: European Journal of Haematology, 2023, v. 110, n. 3. P. 322 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Hoeynck, Brian W.; Cohen, Adam D.; Stadtmauer, Edward A.; Susanibar‐Adaniya, Sandra P.; Vogl, Dan T.; Waxman, Adam J.; Bardsley, Mark; Le, Samantha; LaMaestra, Lexis; Garfall, Alfred L. 3 of 3

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare and often fatal demyelinating disease of the central nervous system caused by reactivation of the JC virus in the context of immune suppression such as HIV, malignancy, and certain immunomodulatory medications. PML has been reported only rarely in multiple myeloma patients, and its presenting features and natural history in this population are not well known. We describe six cases of PML among multiple myeloma patients treated at our institution between 2013 and 2022, including two that developed on or shortly after treatment with recently developed BCMA‐directed immunotherapies. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:European Journal of Haematology. 2023/03, Vol. 110, Issue 3, p322
  • Document Type:Article
  • Subject Area:Consumer Health
  • Publication Date:2023
  • ISSN:0902-4441
  • DOI:10.1111/ejh.13909
  • Accession Number:161658125
  • Copyright Statement:Copyright of European Journal of Haematology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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