JOURNAL ARTICLE

Commentary on: Acute retinal necrosis associated with dimethyl fumarate.

Published In: Multiple Sclerosis Journal, 2025, v. 31, n. 12. P. 1508 1 of 3
Database: Academic Search Ultimate 2 of 3
Authored By: Vidal-Jordana, Angela 3 of 3

Abstract

The article discusses a case involving a 44-year-old man with multiple sclerosis (MS) who developed acute retinal necrosis (ARN) after six years of treatment with dimethyl fumarate (DMF), a disease-modifying therapy. Initially presenting with symptoms such as conjunctival injection and impaired vision, the patient was later diagnosed with a varicella-zoster virus (VZV) infection confirmed by polymerase chain reaction (PCR) testing. The case emphasizes the need for careful consideration of infectious causes for vision loss in MS patients, particularly those on immunosuppressive therapies like DMF, which can increase susceptibility to infections. It also highlights the importance of pre-treatment screening and vaccination strategies to mitigate infection risks in this population. [Extracted from the article]

Additional Information

Source:Multiple Sclerosis Journal. 2025/10, Vol. 31, Issue 12, p1508
Document Type:Article
Subject Area:Consumer Health
Publication Date:2025
ISSN:1352-4585
DOI:10.1177/13524585251326487
Accession Number:188856343
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