JOURNAL ARTICLE

Selenium induces mercury isotope fractionation and detoxification in marine fish.

  • Published In: Environmental Toxicology & Chemistry, 2025, v. 44, n. 1. P. 197 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Cho, Moonkyoung; Lee, Seunghan; Kim, Kang Woong; Besnard, Lucien; Jung, Saebom; Lim, Seung Hyeon; Li, Mi-Ling; Kwon, Sae Yun 3 of 3

Abstract

This article investigates the role of selenium (Se) in mercury (Hg) detoxification in juvenile olive flounders (Paralichthys olivaceus) by using mercury stable isotopes to track internal dynamics of methylmercury (MeHg) and inorganic mercury (IHg) during controlled feeding experiments. The study found that Se facilitates hepatic demethylation of MeHg, converting it into IHg and promoting its excretion, whereas Se plays a relatively minor role in the excretion of IHg. Tissue-specific Hg isotope patterns revealed that the liver is the primary site for Se-induced MeHg demethylation, while intestinal mobilization and redistribution dominate IHg dynamics. These findings highlight the importance of considering Se interactions and tissue-specific processes in ecological risk assessments of mercury exposure in fish.

Additional Information

  • Source:Environmental Toxicology & Chemistry. 2025/01, Vol. 44, Issue 1, p197
  • Document Type:Article
  • Subject Area:Earth and Atmospheric Sciences
  • Publication Date:2025
  • ISSN:0730-7268
  • DOI:10.1093/etojnl/vgae026
  • Accession Number:183714210
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