JOURNAL ARTICLE

In Situ Evaluation of Cellular Spheroid Stiffness by Pinching Device Composed of Piezoactuator and Strain Gauge.

  • Published In: IEEJ Transactions on Electrical & Electronic Engineering, 2023, v. 18, n. 7. P. 1226 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Koyanagi, Kodai; Kusamori, Kosuke; Nishikawa, Makiya; Konishi, Satoshi 3 of 3

Abstract

Mechanical characterization of cells is important for understanding their behavior. This paper reports on an in situ evaluation of the stiffness of cellular spheroids using a pinching device. The pinching device is integrated with a bimorph piezoactuator and strain gauge. It can pinch an object by combining a piezo bimorph actuator and a thin Si structure and can detect the reaction force from an elastic object using a strain gauge integrated into the thin Si structure. The strain gauge can detect the bending deformation of the device and estimate the reaction force by considering actuation. This paper presents the design of the pinching device and experimental results when used for the in situ evaluation of the stiffness of cellular spheroids. © 2023 Institute of Electrical Engineers of Japan. Published by Wiley Periodicals LLC. [ABSTRACT FROM AUTHOR]

Additional Information

  • Source:IEEJ Transactions on Electrical & Electronic Engineering. 2023/07, Vol. 18, Issue 7, p1226
  • Document Type:Article
  • Subject Area:Engineering
  • Publication Date:2023
  • ISSN:1931-4973
  • DOI:10.1002/tee.23794
  • Accession Number:164094746
  • Copyright Statement:Copyright of IEEJ Transactions on Electrical & Electronic Engineering is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.