JOURNAL ARTICLE

Quality of Life Assessment Following Botulinum Toxin Injection in Patients with Adductor Spasmodic Dysphonia Using the 5-Factor Glasgow Benefit Inventory.

  • Published In: Annals of Otology, Rhinology & Laryngology, 2026, v. 135, n. 1. P. 12 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Cirelli Jr., Michael A.; Marino, Michael J.; Lott, David G.; Adler, Charles H.; Bansberg, Stephen F. 3 of 3

Abstract

This article focuses on evaluating patient-reported quality of life (QOL) changes in individuals with adductor spasmodic dysphonia (AdSD) following botulinum neurotoxin type-A (BoNT-A) injections using the revised 5-factor Glasgow Benefit Inventory (GBI-5F). In a cohort of 66 patients, mostly female with an average age of 69, BoNT-A treatment was associated with significant improvements in overall QOL, self-confidence, and social involvement, while general health scores showed no change. The total benefit score correlated moderately with the degree of vocal functional improvement but was not influenced by sex, age, presence of vocal tremor, or duration of post-injection breathiness. The study suggests that the GBI-5F is a useful tool for capturing distinct aspects of patient benefit following BoNT-A treatment in AdSD.

Additional Information

  • Source:Annals of Otology, Rhinology & Laryngology. 2026/01, Vol. 135, Issue 1, p12
  • Document Type:Article
  • Subject Area:Environmental Sciences
  • Publication Date:2026
  • ISSN:0003-4894
  • DOI:10.1177/00034894251356728
  • Accession Number:190221809
  • Copyright Statement:Copyright of Annals of Otology, Rhinology & Laryngology is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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