JOURNAL ARTICLE

Validation and Standardization of Gallic Acid and Ellagic Acid in Quercus Infectoria, Terminalia Chebula, and Pistacia Integerrima.

  • Published In: Journal of AOAC International, 2023, v. 106, n. 5. P. 1305 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Saini, Anil Kumar; Zahiruddin, Sultan; Newton, Kakumani Godwin; Sawant, Laxman; Mitra, Ranjan; Rai, Rajiva Kumar; Ahmad, Sayeed 3 of 3

Abstract

This article focuses on the validation and standardization of gallic acid and ellagic acid in three medicinal plants: Quercus infectoria, Terminalia chebula, and Pistacia integerrima. Due to the threatened status of P. integerrima from overexploitation, Ayurvedic texts recommend Q. infectoria and T. chebula as substitutes based on similar therapeutic properties. The study developed and validated a robust high-performance liquid chromatography (HPLC) method, alongside thin-layer chromatography (TLC) fingerprinting, to comparatively analyze the metabolite profiles and quantify gallic acid and ellagic acid in aqueous and hydroalcoholic extracts of these plants. Results showed comparable phytochemical profiles and measurable amounts of these phenolic compounds across all three species, supporting their potential interchangeability in herbal formulations. The validated methods provide reliable tools for quality control and standardization of these plants in raw materials and commercial herbal products.

Additional Information

  • Source:Journal of AOAC International. 2023/09, Vol. 106, Issue 5, p1305
  • Document Type:Article
  • Subject Area:Environmental Sciences
  • Publication Date:2023
  • ISSN:1060-3271
  • DOI:10.1093/jaoacint/qsad070
  • Accession Number:171801894
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