JOURNAL ARTICLE

Particulate air pollution at the time of oocyte retrieval is independently associated with reduced odds of live birth in subsequent frozen embryo transfers.

  • Published In: Human Reproduction, 2025, v. 40, n. 1. P. 110 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Leathersich, S J; Roche, C S; Walls, M; Nathan, E; Hart, R J 3 of 3

Abstract

This article investigates the impact of particulate matter (PM) air pollution exposure prior to oocyte retrieval and frozen embryo transfer (FET) on live birth rates in assisted reproductive technology (ART). Analyzing 3,659 FET cycles from a single Australian fertility clinic between 2013 and 2021, the study found that higher levels of fine particulate matter (PM₂.₅ and PM₁₀) before oocyte retrieval were associated with significantly reduced odds of live birth, independent of pollution levels at the time of embryo transfer. No consistent effects were observed for gaseous pollutants or pollution exposure around embryo transfer. These findings suggest that even low-level PM exposure during gametogenesis may impair reproductive outcomes, highlighting the need for policies to reduce air pollution to protect fertility.

Additional Information

  • Source:Human Reproduction. 2025/01, Vol. 40, Issue 1, p110
  • Document Type:Article
  • Subject Area:Environmental Sciences
  • Publication Date:2025
  • ISSN:0268-1161
  • DOI:10.1093/humrep/deae259
  • Accession Number:182369109
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