JOURNAL ARTICLE

P‐CB‐9 | High‐Resolution KIR Genotyping of Three Chinese Ethnic Minorities Identifies Distinction of the Tajik Population.

  • Published In: Transfusion, 2023, v. 63, n. S5. P. 151A 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Tao, S.; Wang, J; Zhu, F. 3 of 3

Abstract

The article focuses on the polymorphism of Killer-cell Immunoglobulin-like Receptor (KIR) genes and its impact on the effector activity of cytotoxic natural killer (NK) cells and T cells across different human populations. The study analyzed KIR diversity in three Chinese ethnic minority populations—She, Yugur, and Tajik—comparing them to the majority Zhejiang Han population. Findings revealed that the Tajik population exhibited the highest diversity in gene copy number and allele distribution, with KIR gene patterns reflecting their ancestral origins. The study highlights the influence of demographic and evolutionary factors on KIR diversity, providing insights for future clinical and population research. [Extracted from the article]

Additional Information

  • Source:Transfusion. 2023/10, Vol. 63, Issue S5, p151A
  • Document Type:Article
  • Subject Area:Ethnic and Cultural Studies
  • Publication Date:2023
  • ISSN:0041-1132
  • DOI:10.1111/trf.192_17554
  • Accession Number:191023491
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