JOURNAL ARTICLE

Children's bone age development is delayed with increasing altitude: a multicentre study.

  • Published In: British Journal of Radiology, 2024, v. 97, n. 1164. P. 1931 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Liu, Qixing; Wangjiu, Cidan; Awang, Tudan; Yang, Meijie; Qiongda, Puqiong; Wang, Huogen; Pan, Hui; Wang, Fengdan 3 of 3

Abstract

This study investigates the characteristics of bone age (BA) development in children living at different altitudes and assesses the impact of altitude on BA. Analyzing 1,284 children from Beijing (43.5 m above sea level), Lhasa (3,650 m), and Nagqu (4,500 m), the study used the predicted age difference (PAD)—the difference between BA and chronological age (CA)—to measure growth delay or advancement. Results showed a significant delay in BA with increasing altitude, with PAD values of 0.10 years in Beijing, −0.40 years in Lhasa, and −1.42 years in Nagqu, independent of sex and ethnicity. The findings suggest that high altitude is an independent factor contributing to delayed bone maturation in children, indicating that altitude should be considered when evaluating BA development in pediatric populations residing in high-altitude regions.

Additional Information

  • Source:British Journal of Radiology. 2024/12, Vol. 97, Issue 1164, p1931
  • Document Type:Article
  • Subject Area:Geography and Cartography
  • Publication Date:2024
  • ISSN:0007-1285
  • DOI:10.1093/bjr/tqae168
  • Accession Number:181986897
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