JOURNAL ARTICLE

Clinical profiles and HLA haplotypes in patients with severe cutaneous adverse reactions in Lusaka, Zambia.

  • Published In: International Journal of Dermatology, 2025, v. 64, n. 2. P. 432 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Zulu, Andrew; Pedretti, Sarah; Choshi, Phuti; Peter, Jonathan; Ngalamika, Owen 3 of 3

Abstract

The article explores severe cutaneous adverse reactions (SCARs) in patients in Lusaka, Zambia, focusing on clinical profiles and HLA haplotypes. The study found that SCARs, including SJS/TEN and DRESS, primarily affect young females, with TMP-SMX being a common culprit drug. The research also identified specific HLA haplotypes associated with SJS/TEN cases, suggesting potential for targeted genetic screening in patients with TMP-SMX-induced SCAR. [Extracted from the article]

Additional Information

  • Source:International Journal of Dermatology. 2025/02, Vol. 64, Issue 2, p432
  • Document Type:Article
  • Subject Area:Geography and Cartography
  • Publication Date:2025
  • ISSN:0011-9059
  • DOI:10.1111/ijd.17417
  • Accession Number:183978670
  • Copyright Statement:Copyright of International Journal of Dermatology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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