Prevalence of Chagas disease in Latin American pregnant women in Madrid, Spain: A multicentre cross‐sectional study from 2011 to 2016.

Objective: The aim of this study is to assess Trypanosoma cruzi infection prevalence among pregnant migrants living in Madrid according to the country of origin and to assess screening coverage in this at‐risk population. Methods: Retrospective multicentre cross‐sectional study conducted from January 2011 to December 2016 in eight Madrid hospitals. Each hospital reviewed their microbiology data records to assess the screening coverage and serological diagnosis in all pregnant women coming from endemic areas. Results: From 2011 to 2016, 149,470 deliveries were attended at the eight hospitals, and 11,048 pregnant women were screened for Chagas disease. Most cases (93.5%) were in women from Bolivia, who also showed the highest prevalence (12.4%, 95% confidence interval: 9.9–15.0). Pooled prevalence amongst the screened women was 2.9% (95% CI: 1.8–4.1). Chagas disease screening coverage varied greatly between centres, with a pooled mean coverage of 47% (95% CI: 37%–57%; 73% [95% CI: 63%–82%] for those centres with universal screening vs. 10% [95% CI: 6%–15%] for those with a selective screening approach; p < 0.001). Conclusion: Our study provides useful data for policy makers and epidemiologists in a non‐endemic area without congenital Chagas screening programmes. [ABSTRACT FROM AUTHOR]