Community Health Worker Influence on COVID-19 Vaccine Uptake in New York City, 2021‒2022.

This article evaluates a community health worker (CHW) intervention implemented by the New York City Health Department and community-based organizations (CBOs) to reduce COVID-19 vaccine uptake disparities in 75 historically disinvested, predominantly Black and Latino communities defined by zip codes. Between July 2021 and June 2022, high CHW outreach—characterized by consistent, trauma-informed engagement and culturally tailored education—was associated with a significant increase in vaccine uptake from 44% to 76%, effectively narrowing gaps with better-resourced communities. The intervention included multifaceted outreach activities, referrals to vaccination and social services, and ongoing training for CHWs, highlighting their role in building trust and addressing social determinants of health. Despite higher COVID-19 mortality rates persisting in these communities during the Omicron wave, the intervention contributed to reducing inequities in vaccination and mortality compared to earlier pandemic phases. The study underscores the importance of sustained investment in community-based CHWs and trusted local partnerships for effective public health responses in marginalized populations.