JOURNAL ARTICLE

Outcomes and Practices of Endotracheal Intubation Using the Glasgow Coma Scale in Acute Non-Traumatic Poisoning: A Systematic Review and Meta-Analysis of Proportions.

  • Published In: Journal of Intensive Care Medicine, 2025, v. 40, n. 11. P. 1143 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Nanah, Abdelrahman; Abdeljaleel, Fatima; Matsubara, Júlio Ken; Garcia, Marcos Vinicius Fernandes 3 of 3

Abstract

This article systematically reviews and meta-analyzes endotracheal intubation practices and outcomes in patients with acute non-traumatic poisoning, focusing on the role of the Glasgow Coma Scale (GCS) in guiding airway management. Analyzing 39 studies with 15,959 patients, it found that intubation and aspiration rates were significantly higher in patients with GCS ≤ 8 compared to those with GCS 9–15, while mortality remained low (1–2%) across all groups. The findings challenge the conventional trauma-based threshold of intubating patients with GCS ≤ 8, suggesting that a more individualized approach is needed in acute poisoning cases due to heterogeneity in patient presentations, intoxication types, and clinical practices. The study highlights the need for further research to optimize airway management strategies tailored to this population.

Additional Information

  • Source:Journal of Intensive Care Medicine. 2025/11, Vol. 40, Issue 11, p1143
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2025
  • ISSN:0885-0666
  • DOI:10.1177/08850666241275041
  • Accession Number:188285000
  • Copyright Statement:Copyright of Journal of Intensive Care Medicine is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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