JOURNAL ARTICLE

Reply to: the utility of gallium-68 PET/CT in MEN1 related parathyroid disease.

  • Published In: European Journal of Endocrinology, 2024, v. 191, n. 1. P. L4 1 of 3

  • Database: Academic Search Ultimate 2 of 3

  • Authored By: Kostiainen, Iiro; Schildt, Jukka; Parviainen, Helka; Ryhänen, Eeva M; Schalin-Jäntti, Camilla 3 of 3

Abstract

The article focuses on the effectiveness of somatostatin receptor positron emission tomography/computed tomography (SSTR PET/CT) in diagnosing hyperfunctioning parathyroid glands in patients with multiple endocrine neoplasia type 1 (MEN1). A retrospective analysis of 47 MEN1 patients revealed that SSTR PET/CT had a low sensitivity of 15% for detecting primary hyperparathyroidism (PHPT) pathology, although it demonstrated 100% specificity. The study highlights the limited expression of somatostatin receptors in parathyroid tissue, suggesting that SSTR PET/CT is not suitable for localizing hyperfunctioning parathyroid glands in MEN1, and recommends the use of other imaging techniques for this purpose. [Extracted from the article]

Additional Information

  • Source:European Journal of Endocrinology. 2024/07, Vol. 191, Issue 1, pL4
  • Document Type:Article
  • Subject Area:Health and Medicine
  • Publication Date:2024
  • ISSN:0804-4643
  • DOI:10.1093/ejendo/lvae052
  • Accession Number:178778937
  • Copyright Statement:Copyright of European Journal of Endocrinology is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Looking to go deeper into this topic? Look for more articles on EBSCOhost.