A - 42 Neuropsychological Improvement in Amnestic Mild Cognitive Impairment Following Noninvasive Transcranial Electrical Stimulation: a Case Report.

This article focuses on a case report examining neuropsychological improvements in a 78-year-old male with amnestic Mild Cognitive Impairment (aMCI) following high-definition transcranial direct current stimulation (HD-tDCS), a noninvasive electrical brain stimulation technique. The patient underwent 10 sessions targeting the dorsal anterior cingulate cortex, with assessments on episodic memory, attention, executive function, and language conducted at baseline, immediately post-treatment, and three months later. Significant cognitive improvements were observed immediately after treatment on half of the tests, particularly in visuospatial memory and executive function, but most gains diminished by the three-month follow-up except for immediate visuospatial recall. The report suggests potential therapeutic benefits of HD-tDCS in aMCI but highlights the need for randomized sham-controlled trials to verify efficacy and duration of effects.