Report Summarizes Delirium Study Findings from National Cancer Center Hospital (Potential Effectiveness of Yokukansan and Lemborexant as Alternative Candidates to Benzodiazepines to Prevent Benzodiazepine Withdrawal Delirium in the Cancer...).

The article focuses on the potential effectiveness of yokukansan and lemborexant as alternatives to benzodiazepines for managing benzodiazepine withdrawal delirium in patients undergoing cancer surgery. Research from the National Cancer Center Hospital in Tokyo, Japan, details a case involving an elderly woman who, after ineffective treatment with lorazepam and brotizolam, successfully transitioned to yokukansan and lemborexant, leading to stabilization of her mental status prior to surgery. The findings suggest that these alternatives may help avoid benzodiazepine-related delirium during the cancer perioperative period. The article emphasizes the importance of considering gradual replacement or reduction of benzodiazepines in similar clinical scenarios. [Extracted from the article]